Well, according to Martin Whitmarsh, McLaren were a pioneer in this field and it has brought them a lot. But it hasn't brought them too much success, with 'only' 3 WDCs and 2 WCCs in 11 seasons.
I liked EJ's statement, though, on the 6 million simulations you run, and the race often pans out quite differently. I, too, believe there's nothing to substitute experience and on-track insight into races.